Aspergillus galactomannan detection in comparison to a real-time PCR assay in serum samples from a high-risk group of patients
نویسندگان
چکیده
Invasive aspergillosis (IA) is a severe infection with a 70% mortality rate. Aspergillus fumigatus is responsible for over 90% of those infections. The diagnosis of invasive aspergillosis is based on clinical sample culture and detection of fungal hyphae in histopathological examination. Additional tests may include the detection of the galactomannan antigen and of fungal genetic material in serum and bronchoalveolar washings. The present study was to assess the use of these two rapid tests in the diagnosis of invasive aspergillosis: serological one - to detect the galactomannan antigen (ELISA assay), and real-time PCR, and to establish a possible correlation between these two methods.
منابع مشابه
Comments on \'\'Detection of galactomannan in the bronchoalveolar lavage of high-risk patients with invasive aspergillosis admitted at the intensive care unit\'\' by Khodavaisy et al.
Comments on ''Detection of galactomannan in the bronchoalveolar lavage of high-risk patients with invasive aspergillosis admitted at the intensive care unit'' by Khodavaisy et al. AWT-SEP AWT-SEP AWT-SEP AWT-SEP AWT-SEP AWT-SEP Galactomannan in bronchoalveolar lavage for diagnosis of invasive aspergillosis We rea...
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